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Ligand · DZA

DZA · Daminozide

DZA, Daminozide (C6 H12 N2 O3, 160.2 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DZA
Formula
C6 H12 N2 O3
Class
ligand
Structures
7
PDB entries
4

Binding sites

DZA in 7 structures; the first of them:

  • 4AI8 · Factor inhibiting hif-1 alpha in complex with daminozide · DZA A1358 · binds TYR145, LEU188, THR196, HIS199, ASP201, ASN205, PHE207, LYS214 and 4 more
  • 4AI9 · JMJD2A Complexed with Daminozide · DZA A601 · binds GLU23, ARG29, TYR30, TYR33, PHE353
  • 4DO0 · Crystal Structure of human PHF8 in complex with Daminozide · DZA A501 · binds ASN189, ILE191, LEU236, THR244, HIS247, ASP249, PHE250, TYR257 and 4 more
  • 8S4C · CdaA-H04 complex · DZA B201 · binds GLN9, LEU12, VAL34, ALA35, ARG36, ASP37, GLY78, LEU153 and 1 more
  • 4AI8 · Factor inhibiting hif-1 alpha in complex with daminozide · DZA A1358 · binds TYR145, LEU188, THR196, HIS199, ASP201, ASN205, PHE207, LYS214 and 4 more
  • 4AI9 · JMJD2A complexed with daminozide · DZA A601 · binds GLU23, ARG29, TYR30, TYR33, PHE353
  • 4DO0 · Crystal structure of human PHF8 in complex with daminozide · DZA A501 · binds ASN189, ILE191, LEU236, THR244, HIS247, ASP249, PHE250, TYR257 and 4 more

Residues it binds most

HIS 8, TYR 10, ASN 8, LYS 8, PHE 10, SER 4, THR 7, GLU 6, ILE 4, LEU 5 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol
  • NI · Nickel (II) ion
  • CL · Chloride ion
  • ACT · Acetate ion
  • EDO · 1,2-ethanediol

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