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Ligand · DOL

DOL · 5-(2-diethylamino-ethanesulfonyl)-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triaza-tricyclo[23.2.1.00,255]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetraone

DOL, 5-(2-diethylamino-ethanesulfonyl)-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triaza-tricyclo[23.2.1.00,255]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetraone (C34 H50 N4 O9 S, 690.9 g/mol), in the MolNFT…

Component
DOL
Formula
C34 H50 N4 O9 S
Class
ligand
Structures
3
PDB entries
3

Binding sites

DOL in 3 structures; the first of them:

  • 6ZS9 · Human mitochondrial ribosome in complex with ribosome recycling factor · DOL XA5141 · binds G2724, A2725, C2726, A2938, C2939, A2990, U2991, G2992 and 4 more
  • 6ZSB · Human mitochondrial ribosome in complex with mRNA and P-site tRNA · DOL XA5143 · binds G2724, A2725, C2726, A2938, C2939, A2990, U2991, G2992 and 4 more
  • 6ZSC · Human mitochondrial ribosome in complex with E-site tRNA · DOL XA5144 · binds G2724, A2725, C2726, A2938, C2939, A2990, U2991, G2992 and 4 more

Residues it binds most

U 3, A 3, C 3, G 3, DBB 2, P5P 1 (residue and the binding sites it lines).

Found with

  • GTP · Guanosine-5'-triphosphate
  • MG · Magnesium ion
  • ZN · Zinc ion

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