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Ligand · DHI

DHI · D-histidine

DHI, D-histidine (C6 H10 N3 O2 +1, 156.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DHI
Formula
C6 H10 N3 O2 +1
Class
ligand
Structures
8
PDB entries
4

Binding sites

DHI in 8 structures; the first of them:

  • 2EZ7 · Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII and XIV with L… · DHI A301 · binds HIS4, TRP5, HIS64, ASN67, GLN92, THR200, PRO201, PRO202
  • 3KL3 · Crystal structure of Ligand bound XynC · DHI A403 · binds PRO299, GLY300, TYR301, GLY321, ASP322, ASN323
  • 3KOC · DTD from Plasmodium falciparum in complex with D-Histidine · DHI C165 · binds PHE89, PRO109, GLY138, ASN139, TYR140
  • 6H3D · Staphylopine dehydrogenase in complex with xNA · DHI A601 · binds TYR240, ASN285, TYR286, ARG316, ILE320, PHE337, VAL340
  • 2EZ7 · Carbonic anhydrase activators. activation of isozymes I, II, IV, va, VII and xiv with L… · DHI A301 · binds HIS4, TRP5, HIS64, ASN67, GLN92, THR200, PRO201, PRO202
  • 3KL3 · Crystal structure of ligand bound xync · DHI A403 · binds PRO299, GLY300, TYR301, GLY321, ASP322, ASN323
  • 3KOC · Dtd from plasmodium falciparum in complex with D-histidine · DHI C165 · binds PHE89, PRO109, GLY138, ASN139, TYR140
  • 6H3D · Staphylopine dehydrogenase in complex with xna · DHI A601 · binds TYR240, ASN285, TYR286, ARG316, ILE320, PHE337, VAL340

Residues it binds most

TYR 8, GLY 8, PRO 8, ASN 8, PHE 8, GLN 4, HIS 2, ARG 2, ASP 2, GLU 2 (residue and the binding sites it lines).

Found with

  • PG4 · Tetraethylene glycol
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • HG · Mercury (II) ion
  • ZN · Zinc ion
  • BDP · beta-D-glucopyranuronic acid
  • GCU · alpha-D-glucopyranuronic acid
  • GOL · Glycerol

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