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Ligand · DGY

DGY · (2R)-2,3-dihydroxypropanoic acid

DGY, (2R)-2,3-dihydroxypropanoic acid (C3 H6 O4, 106.1 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
DGY
Formula
C3 H6 O4
Class
ligand
Structures
8
PDB entries
4

Binding sites

DGY in 8 structures; the first of them:

  • 2BO6 · Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase · DGY A1382 · binds ARG131, ASP135, ALA136, MET137, ILE138, THR139, LEU163, LEU226 and 1 more
  • 2GCG · Ternary Crystal Structure of Human Glyoxylate Reductase/Hydroxypyruvate Reductase · DGY A3001 · binds LEU59, SER82, VAL83, GLY84, LEU107, ARG245, HIS293, SER296 and 2 more
  • 3VAZ · Crystal structure of Staphylococcal GAPDH1 in a hexagonal space group · DGY O403 · binds ASP165, ASP166
  • 4WVC · Crystal structure of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8 in… · DGY A502 · binds TYR28, TRP32, HIS71, TYR81, GLN103, TRP160, ASP165, ARG198 and 2 more
  • 2BO6 · Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase · DGY A1382 · binds ARG131, ASP135, ALA136, MET137, ILE138, THR139, LEU163, LEU226 and 1 more
  • 2GCG · Ternary crystal structure of human glyoxylate REDUCTASE/HYDROXYPYRUVATE reductase · DGY A3001 · binds LEU59, SER82, VAL83, GLY84, LEU107, ARG245, HIS293, SER296 and 2 more
  • 3VAZ · Crystal structure of staphylococcal GAPDH1 in a hexagonal space group · DGY O403 · binds ASP165, ASP166
  • 4WVC · Crystal structure of GH63 mannosylglycerate hydrolase from thermus thermophilus HB8 in… · DGY A502 · binds TYR28, TRP32, HIS71, TYR81, GLN103, TRP160, ASP165, ARG198 and 2 more

Residues it binds most

ASP 12, LEU 8, TYR 4, ARG 12, MET 8, TRP 8, HIS 8, SER 4, GLY 6, ALA 4 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • MN · Manganese (II) ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • SO4 · Sulfate ion
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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