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Ligand · DAR

DAR · D-arginine

DAR, D-arginine (C6 H15 N4 O2 +1, 175.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DAR
Formula
C6 H15 N4 O2 +1
Class
ligand
Structures
8
PDB entries
8

Binding sites

DAR in 8 structures; the first of them:

  • 1BG0 · Transition state structure of arginine kinase · DAR A403 · binds SER63, GLY64, VAL65, GLY66, TYR68, PHE194, GLU225, CYS271 and 4 more
  • 1P52 · Structure of Arginine kinase E314D mutant · DAR A403 · binds SER63, GLY64, VAL65, GLY66, TYR68, PHE194, GLU225, CYS271 and 5 more
  • 6MP8 · X-ray crystal structure of VioC bound to Fe(II), D-arginine, and 2-oxoglutarate · DAR A403 · binds GLN137, LEU156, VAL157, SER158, LEU165, GLY166, TRP167, HIS168 and 5 more
  • 6P2I · Acyclic imino acid reductase (Bsp5) in complex with NADPH and D-Arg · DAR A402 · binds THR10, GLU51, ILE72, THR73, THR74, SER75, TYR97, ARG229 and 3 more
  • 6SCK · Thermolysin in complex with fragment J77 · DAR E413 · binds TYR193, SER201, LEU202, ARG203, TYR211, ASP213, HIS231, ILE232
  • 7AC9 · Thrombin in complex with D-arginine (j77) · DAR H306 · binds ASP189, ALA190, CYS191, GLU192, GLY193, ASP194, SER195, VAL213 and 6 more
  • 7YW9 · Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG · DAR A405 · binds GLN117, GLN136, VAL137, GLY138, LEU145, GLY146, TRP147, HIS148 and 8 more
  • 8BSA · Vc1313-LBD bound to D-arginine · DAR A301 · binds ASN43, ASP47, THR48, ALA51, TYR102, THR105, VAL106, TRP107 and 4 more

Residues it binds most

THR 6, GLY 5, TYR 8, ASP 7, GLU 9, SER 8, ASN 6, TRP 7, VAL 7, ARG 6 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate
  • MG · Magnesium ion
  • NO3 · Nitrate ion
  • DMS · Dimethyl sulfoxide
  • AKG · 2-oxoglutaric acid
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • CA · Calcium ion
  • FE2 · Fe (II) ion
  • NA · Sodium ion
  • ZN · Zinc ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • PO4 · Phosphate ion

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