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Ligand · D1Z

D1Z · ~{N}-[[(3~{R})-5-[5-[[3-[(dimethylamino) methyl]phenyl]amino]-6-methoxy-pyridin-2-yl]-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]oxane-4-carboxamide

D1Z, ~{N}-[[(3~{R})-5-[5-[[3-[(dimethylamino) methyl]phenyl]amino]-6-methoxy-pyridin-2-yl]-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]oxane-4-carboxamide (C30 H36 N4 O5, 532.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
D1Z
Formula
C30 H36 N4 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

D1Z in 2 structures; the first of them:

  • 6FA3 · Antibody derived (Abd-6) small molecule binding to KRAS. · D1Z B203 · binds LYS5, LEU6, VAL7, SER39, TYR40, ARG41, ASP54, ILE55 and 9 more
  • 6FA3 · Antibody derived (abd-6) small molecule binding to KRAS. · D1Z B203 · binds LYS5, LEU6, VAL7, SER39, TYR40, ARG41, ASP54, ILE55 and 8 more

Residues it binds most

TYR 8, LEU 8, GLN 7, ASP 8, GLU 7, THR 8, ARG 8, GLY 8, LYS 8, MET 6 (residue and the binding sites it lines).

Found with

  • GNP · Phosphoaminophosphonic acid-guanylate ester
  • MG · Magnesium ion
  • DMS · Dimethyl sulfoxide

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