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Ligand · CYT

CYT · 6-aminopyrimidin-2(1H)-one

CYT, 6-aminopyrimidin-2(1H)-one (C4 H5 N3 O, 111.1 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
CYT
Formula
C4 H5 N3 O
Class
ligand
Structures
12
PDB entries
8

Binding sites

CYT in 12 structures; the first of them:

  • 5EFO · X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytidine and… · CYT A302 · binds GLY95, PHE161, GLN165, ARG167, PHE194, GLU195, MET196
  • 5EPU · X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytosine at… · CYT A301 · binds THR93, THR94, GLY95, PHE161, GLN165, ARG167, PHE194, GLU195 and 1 more
  • 5ERE · Extracellular ligand binding receptor from Desulfohalobium retbaense DSM5692 · CYT A602 · binds ASN411, VAL413, ILE421, ILE437, GLN440, GLN442, MSE460, VAL461 and 5 more
  • 5KO5 · Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5KO6 · Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5LOK · X-ray structure of uridine phosphorylase from Vibrio cholerae in complex with cytidine… · CYT A304 · binds THR93, THR94, GLY95, PHE161, GLN165, ARG167, PHE194, GLU195 and 4 more
  • 7QOA · Structure of CodB, a cytosine transporter in an outward-facing conformation · CYT A501 · binds PHE33, GLN105, TRP108, SER203, PHE204, ILE205, SER206, ALA207 and 2 more
  • 9GN2 · Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Complex with ribose… · CYT A201 · binds TRP12, PHE13, PRO42, GLN46, VAL52, TRP64, THR68, ASP72 and 5 more
  • 5KO5 · Crystal structure of isoform 2 of purine nucleoside phosphorylase from schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5KO6 · Crystal structure of isoform 2 of purine nucleoside phosphorylase from schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5LOK · X-ray structure of uridine phosphorylase from vibrio cholerae in complex with cytidine… · CYT A304 · binds THR93, THR94, GLY95, PHE161, GLN165, ARG167, PHE194, GLU195 and 3 more
  • 7QOA · Structure of codb, a cytosine transporter in an outward-facing conformation · CYT A501 · binds PHE33, GLN105, TRP108, SER203, PHE204, SER206, ALA207, THR279

Residues it binds most

PHE 29, THR 25, ILE 24, GLU 30, GLY 27, GLN 28, ARG 24, MET 27, SER 11, ALA 8 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • NA · Sodium ion
  • CTN · 4-amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone
  • CL · Chloride ion
  • A6L · 2,3-dihydroxypropyl (9Z)-octadec-9-enoate
  • PEF · Di-palmitoyl-3-sn-phosphatidylethanolamine
  • R1P · 1-O-phosphono-alpha-D-ribofuranose
  • K · Potassium ion
  • SO4 · Sulfate ion
  • LMT · Dodecyl-beta-D-maltoside
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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