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Ligand · CYT

CYT · 6-aminopyrimidin-2(1H)-one

CYT, 6-aminopyrimidin-2(1H)-one (C4 H5 N3 O, 111.1 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
CYT
Formula
C4 H5 N3 O
Class
ligand
Structures
8
PDB entries
6

Binding sites

CYT in 8 structures; the first of them:

  • 5EFO · X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytidine and… · CYT A302 · binds GLY95, PHE161, GLN165, ARG167, PHE194, GLU195, MET196
  • 5EPU · X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytosine at… · CYT A301 · binds THR93, THR94, GLY95, PHE161, GLN165, ARG167, PHE194, GLU195 and 1 more
  • 5KO5 · Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5KO6 · Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5KO5 · Crystal structure of isoform 2 of purine nucleoside phosphorylase from schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5KO6 · Crystal structure of isoform 2 of purine nucleoside phosphorylase from schistosoma… · CYT A301 · binds LEU118, ALA119, GLY120, TYR202, GLU203, VAL219, GLY220, MET221 and 4 more
  • 5LOK · X-ray structure of uridine phosphorylase from vibrio cholerae in complex with cytidine… · CYT A304 · binds THR93, THR94, GLY95, PHE161, GLN165, ARG167, PHE194, GLU195 and 3 more
  • 7QOA · Structure of codb, a cytosine transporter in an outward-facing conformation · CYT A501 · binds PHE33, GLN105, TRP108, SER203, PHE204, SER206, ALA207, THR279

Residues it binds most

PHE 20, THR 16, GLY 20, GLU 22, ILE 15, ARG 18, MET 20, GLN 18, SER 8, ALA 6 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • NA · Sodium ion
  • GOL · Glycerol
  • CTN · 4-amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone
  • R1P · 1-O-phosphono-alpha-D-ribofuranose
  • CL · Chloride ion
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol
  • A6L · 2,3-dihydroxypropyl (9Z)-octadec-9-enoate
  • PEF · Di-palmitoyl-3-sn-phosphatidylethanolamine
  • K · Potassium ion
  • MG · Magnesium ion
  • SO4 · Sulfate ion

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