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Ligand · CTN

CTN · 4-amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone

CTN, 4-amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone (C9 H13 N3 O5, 243.2 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (11 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
CTN
Formula
C9 H13 N3 O5
Class
ligand
Structures
16
PDB entries
11

Binding sites

CTN in 16 structures; the first of them:

  • 5CSO · Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina… · CTN A804 · binds TYR70, ILE71, MET72, PHE83, GLU85, GLY109, ASN110, TYR111 and 4 more
  • 5EFO · X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytidine and… · CTN E303 · binds THR93, THR94, GLY95, PHE161, GLN165, ARG167, PHE194, GLU195 and 5 more
  • 5TBT · Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with Cytidine · CTN A301 · binds SER35, HIS88, TYR90, LEU118, ALA119, GLY120, TYR202, GLU203 and 6 more
  • 5W1C · Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex… · CTN B2002 · binds ARG1025, GLU1026, THR1027, ASN1051, HIS1056, TRP1084, SER1085, PRO1086 and 2 more
  • 6CVU · Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with… · CTN A303 · binds GLY12, VAL13, GLY14, VAL17, GLU52, GLY169, SER170, LEU196 and 5 more
  • 6YA4 · Crystal structure of PnrA from S. pneumoniae in complex with cytidine · CTN C401 · binds ASP28, THR29, ASP34, PHE37, ASN38, GLY89, PHE90, ASP112 and 10 more
  • 7VTF · cytidine bound structure of Pseudouridine kinase (PUKI) from Escherichia coli strain B · CTN A401 · binds SER12, ASN14, ASP16, GLY40, GLY41, VAL42, ASN45, TYR97 and 7 more
  • 8J5F · Crystal structure of kinase AbmG in complex with cytidine and ADP · CTN A301 · binds THR43, GLU70, ARG71, HIS74, LEU78, MET81, PHE82, GLN93 and 9 more
  • 9GN4 · Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Y7F/D72N mutant… · CTN A201 · binds PHE7, PHE8, GLY9, ALA10, GLY11, TRP12, PHE13, PRO42 and 12 more
  • 5LOK · X-ray structure of uridine phosphorylase from vibrio cholerae in complex with cytidine… · CTN A303 · binds ILE68, ARG90, THR93, THR94, GLY95, PHE161, GLN165, ARG167 and 6 more
  • 5TBT · Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with cytidine · CTN A301 · binds SER35, HIS88, TYR90, LEU118, GLY120, TYR202, GLU203, VAL219 and 4 more
  • 5W1C · Crystal structure of mbp fused activation-induced cytidine deaminase (aid) in complex… · CTN B2002 · binds ARG1025, THR1027, ASN1051, HIS1056, TRP1084, SER1085, PRO1086, CYS1087 and 1 more
  • 6CVU · Crystal structure of mycobacterium tuberculosis dethiobiotin synthetase in complex with… · CTN A303 · binds GLY12, VAL13, GLY14, VAL17, GLU52, GLY169, SER170, LEU196 and 4 more
  • 6NN0 · Crystal structure of mycobacterium tuberculosis dethiobiotin synthetase in complex with… · CTN B303 · binds GLY12, VAL17, GLY169, SER170, LEU196, PRO197, GLY199, ALA200 and 1 more
  • 6YA4 · Crystal structure of pnra from S. pneumoniae in complex with cytidine · CTN C401 · binds ASP28, THR29, PHE37, ASN38, PHE90, ASP112, VAL158, ILE159 and 8 more

Residues it binds most

GLY 39, PHE 20, VAL 28, ASP 19, ASN 23, ALA 21, THR 27, GLU 22, SER 24, ILE 17 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether
  • CYT · 6-aminopyrimidin-2(1H)-one
  • CA · Calcium ion
  • NI · Nickel (II) ion
  • ZN · Zinc ion
  • ACT · Acetate ion
  • EDO · 1,2-ethanediol
  • ADP · Adenosine-5'-diphosphate
  • KSJ · [(1S,2R)-2-(2-hydroxybenzene-1-carbonyl) cyclopentyl]acetic acid
  • KSP · [(1R,2S)-2-(2-hydroxybenzene-1-carbonyl) cyclopentyl]acetic acid

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