GL1X · GenesisL1 explorer

Ligand · CIH

CIH · (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide

CIH, (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide (C17 H12 Cl2 N2 O2, 347.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
CIH
Formula
C17 H12 Cl2 N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

CIH in 2 structures; the first of them:

  • 3FJ6 · Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2 · CIH A399 · binds TYR38, LEU42, MET43, LEU46, PRO52, ALA55, HIS56, ALA59 and 13 more
  • 3FJ6 · Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2 · CIH A399 · binds TYR38, LEU42, MET43, LEU46, PRO52, ALA55, HIS56, ALA59 and 13 more

Residues it binds most

LEU 2, PRO 2, ALA 2, MET 2, PHE 2, THR 2, TYR 2, ARG 2, GLY 2, HIS 2 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • ORO · Orotic acid
  • SO4 · Sulfate ion
  • ACT · Acetate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.