BW0 · [[(2~{R},3~{S},4~{R},5~{R})-5-[(4~{E})-4-[(4-methoxycarbonylphenyl)methoxyimino]-3-methyl-2-oxidanylidene-pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid

Binding sites

BW0 in 4 structures; the first of them:

• 7QGL · Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl-CMPCP derivative… · BW0 A604 · binds ASP47, SER49, LYS50, ARG354, ASN390, GLY392, GLY393, ARG395 and 5 more
• 7QGO · Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl-CMPCP derivative… · BW0 A603 · binds ASP36, HIS38, ASP85, GLN88, ASN117, HIS118, ASP121, ASN122 and 17 more
• 7QGL · Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl- cmpcp derivative… · BW0 A604 · binds ASP47, SER49, ARG354, ASN390, GLY392, GLY393, ARG395, PRO416 and 4 more
• 7QGO · Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl- cmpcp derivative… · BW0 A603 · binds ASP36, HIS38, ASP85, GLN88, ASN117, HIS118, ASP121, LEU184 and 11 more

Residues it binds most

ASP 4, GLY 4, ASN 4, ARG 4, PHE 4, HIS 2, PRO 3, SER 3, GLN 2, LEU 2 (residue and the binding sites it lines).

Found with

• ZN · Zinc ion
• CA · Calcium ion
• 1PE · Pentaethylene glycol