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Ligand · BTX

BTX · ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methyl 5-((3as,4s,6ar)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentyl hydrogen phosphate

BTX, ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methyl 5-((3as,4s,6ar)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentyl hydrogen phosphate (C20 H30 N7 O8 P S, 559.5 g/mol), in the MolNFT structures on…

Component
BTX
Formula
C20 H30 N7 O8 P S
Class
ligand
Structures
8
PDB entries
4

Binding sites

BTX in 8 structures; the first of them:

  • 2E41 · Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with the… · BTX A1301 · binds SER21, THR22, ASN23, GLN42, MET44, GLY45, HIS46, GLY47 and 20 more
  • 2EWN · Ecoli Biotin Repressor with co-repressor analog · BTX A501 · binds SER89, THR90, ASN91, GLN112, ALA114, GLY115, ARG116, GLY117 and 24 more
  • 4DQ2 · Structure of staphylococcus aureus biotin protein ligase in complex with biotinol-5'-amp · BTX A500 · binds SER93, THR94, GLN95, GLN116, LYS118, GLY119, ARG120, GLY121 and 22 more
  • 4WF2 · Structure of E. coli BirA G142A bound to biotinol-5'-AMP · BTX A501 · binds SER89, THR90, ASN91, GLN112, ALA114, GLY115, ARG116, GLY117 and 19 more
  • 2E41 · Crystal structure of biotin protein ligase from pyrococcus horikoshii complexed with the… · BTX A1301 · binds SER21, THR22, ASN23, GLN42, MET44, GLY45, HIS46, GLY47 and 20 more
  • 2EWN · Ecoli biotin repressor with co-repressor analog · BTX A501 · binds SER89, THR90, ASN91, GLN112, ALA114, GLY115, ARG116, GLY117 and 24 more
  • 4DQ2 · Structure of staphylococcus aureus biotin protein ligase in complex with biotinol-5'-AMP · BTX A500 · binds SER93, THR94, GLN95, GLN116, LYS118, GLY119, ARG120, GLY121 and 22 more
  • 4WF2 · Structure of E. COLI bira G142A bound to biotinol-5'-AMP · BTX A501 · binds SER89, THR90, ASN91, GLN112, ALA114, GLY115, ARG116, GLY117 and 19 more

Residues it binds most

GLY 12, ASN 12, ARG 12, ALA 12, SER 12, LYS 12, TRP 12, LEU 12, GLN 12, ILE 12 (residue and the binding sites it lines).

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