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Ligand · AXP

AXP · (1S)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol

AXP, (1S)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol (C10 H20 N O9 P, 329.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5…

Component
AXP
Formula
C10 H20 N O9 P
Class
sugar
Structures
4
PDB entries
2

Binding sites

AXP in 4 structures; the first of them:

  • 1DIL · Sialidase from salmonella typhimurium complexed with apana and epana inhibitors · AXP A384 · binds ARG37, ILE38, ARG56, ASP62, GLN63, MET99, ASP100, TRP121 and 8 more
  • 1INW · A sialic acid derived phosphonate analog inhibits different strains of influenza virus… · AXP A500 · binds ARG118, GLU119, ASP151, ARG152, ARG156, TRP178, SER179, ILE222 and 8 more
  • 1DIL · Sialidase from salmonella typhimurium complexed with apana and epana inhibitors · AXP A384 · binds ARG37, ILE38, ARG56, ASP62, GLN63, MET99, ASP100, TRP121 and 8 more
  • 1INW · A sialic acid derived phosphonate analog inhibits different strains of influenza virus… · AXP A500 · binds ARG118, GLU119, ASP151, ARG152, ARG156, TRP178, SER179, ILE222 and 8 more

Residues it binds most

ARG 4, GLU 4, ASP 4, TRP 4, TYR 4, ILE 4, ALA 2, ASN 2, GLN 2, LEU 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • K · Potassium ion
  • EQP · (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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