GL1X · GenesisL1 explorer

Ligand · AFN

AFN · 8,9-dihydro-9-hydroxy-aflatoxin B1

AFN, 8,9-dihydro-9-hydroxy-aflatoxin B1 (C17 H14 O7, 330.3 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
AFN
Formula
C17 H14 O7
Class
ligand
Structures
11
PDB entries
7

Binding sites

AFN in 11 structures; the first of them:

  • 1AG5 · The solution structure of an aflatoxin B1 epoxide adduct at the N7 position of guanine… · AFN A11 · binds DC5, DG6, DA7, DA16, DG17
  • 1MK6 · Solution structure of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B1 adduct… · AFN A11 · binds DC5, DG6, DA15, DG16
  • 1MKL · NMR refined structure of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B1 adduct in a… · AFN A11 · binds DC5, DG6, DC15, DG16
  • 1N1N · Structure of Mispairing of the Deoxycytosine with Deoxyadenosine 5' to the… · AFN A26 · binds DC5, DG6, DC15, DA16
  • 3PW4 · Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV… · AFN B387 · binds ARG333, DT373, DG374, DC359
  • 3PW5 · Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV… · AFN B387 · binds TYR13, LYS79, ARG333, DT373, DG374, DC359
  • 3PW7 · Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV… · AFN B387 · binds TYR15, VAL35, ALA45, VAL46, ALA47, ALA60, GLY61, MET79 and 2 more
  • 1AG5 · The solution structure of an aflatoxin B1 epoxide adduct at the N7 position of guanine… · AFN A11 · binds DC5, DG6, DA7, DA16, DG17
  • 1MK6 · Solution structure of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy- aflatoxin B1 adduct… · AFN A11 · binds DC5, DG6, DA15, DG16
  • 1MKL · NMR refined structure of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy- aflatoxin B1 adduct in… · AFN A11 · binds DC5, DG6, DC15, DG16
  • 1N1N · Structure of mispairing of the deoxycytosine with deoxyadenosine 5' to the… · AFN A26 · binds DC5, DG6, DC15, DA16

Residues it binds most

DG 12, DC 10, DA 6, ALA 2, DT 4, VAL 2, TYR 3, ARG 2, GLY 2, MET 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • DCP · 2'-deoxycytidine-5'-triphosphate
  • DTP · 2'-deoxyadenosine 5'-triphosphate
  • TTP · Thymidine-5'-triphosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.