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Ligand · ADI

ADI · 2',3'-dideoxyadenosine-5'-diphosphate

ADI, 2',3'-dideoxyadenosine-5'-diphosphate (C10 H15 N5 O8 P2, 395.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
ADI
Formula
C10 H15 N5 O8 P2
Class
ligand
Structures
4
PDB entries
2

Binding sites

ADI in 4 structures; the first of them:

  • 1JX4 · Crystal Structure of a Y-family DNA Polymerase in a Ternary Complex with DNA Substrates… · ADI A1014 · binds DA13, DT5, DT6, ASP7, PHE8, ASP9, TYR10, PHE11 and 12 more
  • 3GV5 · Human DNA polymerase iota in complex with T template DNA and incoming ddADP · ADI B425 · binds ASP34, LEU35, ASP36, CYS37, PHE38, VAL64, THR65, TYR68 and 8 more
  • 1JX4 · Crystal structure of a Y-family DNA polymerase in a ternary complex with DNA substrates… · ADI A1014 · binds DA13, DT5, DT6, ASP7, PHE8, ASP9, TYR10, PHE11 and 12 more
  • 3GV5 · Human DNA polymerase iota in complex with T template DNA and incoming ddadp · ADI B425 · binds ASP34, LEU35, ASP36, CYS37, PHE38, VAL64, THR65, TYR68 and 8 more

Residues it binds most

ASP 6, DT 6, LYS 6, TYR 6, LEU 4, PHE 6, ARG 6, THR 6, VAL 6, ALA 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • MG · Magnesium ion
  • GOL · Glycerol

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