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Ligand · A4F

A4F · 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

A4F, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid (C20 H13 N O5, 347.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
A4F
Formula
C20 H13 N O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

A4F in 2 structures; the first of them:

  • 4ZS3 · Structural complex of 5-aminofluorescein bound to the FTO protein · A4F A602 · binds VAL83, ILE85, LEU90, LEU91, THR92, PRO93, ARG96, TYR108 and 6 more
  • 4ZS3 · Structural complex of 5-aminofluorescein bound to the fto protein · A4F A602 · binds VAL83, ILE85, LEU90, LEU91, THR92, PRO93, ARG96, TYR108 and 6 more

Residues it binds most

LEU 2, VAL 2, ALA 2, ARG 2, HIS 2, ILE 2, PRO 2, SER 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • AKG · 2-oxoglutaric acid
  • MN · Manganese (II) ion

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