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Ligand · A4C

A4C · 9,9'-(hexane-1,6-diyldiimino)bis{n-[2-(dimethylamino)ethyl]acridine-4-carboxamide}

A4C, 9,9'-(hexane-1,6-diyldiimino)bis{n-[2-(dimethylamino)ethyl]acridine-4-carboxamide} (C42 H50 N8 O2, 698.9 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within…

Component
A4C
Formula
C42 H50 N8 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

A4C in 4 structures; the first of them:

  • 2GB9 · d(CGTACG)2 crosslinked bis-acridine complex · A4C B301 · binds DA4, DC5, DG6, DC1, DG2, DT3
  • 2GWA · Crystal Structure of a Complex Formed Between the DNA Holliday Junction and a… · A4C A11 · binds DT5, DA6, DC7, DG4, DT5, DA6, DC7
  • 2GB9 · D(CGTACG)2 crosslinked bis-acridine complex · A4C B301 · binds DA4, DC5, DG6, DC1, DG2, DT3
  • 2GWA · Crystal structure of a complex formed between the DNA holliday junction and a… · A4C A11 · binds DT5, DA6, DC7, DG4, DT5, DA6, DC7

Residues it binds most

DC 6, DG 6, DA 4, DT 4 (residue and the binding sites it lines).

Found with

  • SPM · Spermine
  • SR · Strontium ion

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