Ligand · A26
A26 · (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
A26, (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide (C12 H9 F3 N2 O2, 270.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- A26
- Formula
- C12 H9 F3 N2 O2
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
A26 in 4 structures; the first of them:
- 1D3H · Human dihydroorotate dehydrogenase complexed with antiproliferative agent A771726 · A26 A397 · binds MET43, PRO52, ALA55, HIS56, ALA59, THR63, PHE98, MET111 and 7 more
- 1TV5 · Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor · A26 A1001 · binds TYR168, PHE171, LEU172, CYS175, GLY181, CYS184, HIS185, PHE188 and 8 more
- 1D3H · Human dihydroorotate dehydrogenase complexed with antiproliferative agent A771726 · A26 A397 · binds MET43, PRO52, ALA55, HIS56, ALA59, THR63, PHE98, MET111 and 7 more
- 1TV5 · Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor · A26 A1001 · binds TYR168, PHE171, LEU172, CYS175, GLY181, CYS184, HIS185, PHE188 and 8 more
Residues it binds most
PHE 4, GLY 4, LEU 4, MET 4, TYR 4, ALA 2, ARG 4, CYS 2, HIS 4, PRO 2 (residue and the binding sites it lines).
Found with
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