Ligand · A1N
A1N · (2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine
A1N, (2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine (C21 H25 N5 O2, 379.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with…
- Component
- A1N
- Formula
- C21 H25 N5 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 2
Binding sites
A1N in 2 structures; the first of them:
- 9CHO · Autoinhibited full-length LRRK2(I2020T) on microtubules with MLi-2 · A1N A2701 · binds LEU1885, GLY1886, ASP1887, GLY1888, VAL1893, ARG1895, GLU1902, ALA1904 and 13 more
- 5OPB · Structure of CHK1 10-pt. mutant complex with indazole LRRK2 inhibitor · A1N A301 · binds LEU15, GLU17, GLY18, VAL23, ALA36, MET84, GLU85, LEU86 and 7 more
Residues it binds most
ALA 2, LEU 2, GLY 2, GLU 2, SER 2, ARG 1, ASN 2, HIS 2, MET 2, VAL 2 (residue and the binding sites it lines).
Found with
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