Ligand · A1AEI
A1AEI · 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine
A1AEI, 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine (C13 H10 F3 N7, 321.3 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (5 PDB entries). Every binding site with its residues within…
- Component
- A1AEI
- Formula
- C13 H10 F3 N7
- Class
- ligand
- Structures
- 5
- PDB entries
- 5
Binding sites
A1AEI in 5 structures; the first of them:
- 8VY7 · CryoEM structure of Gi-coupled TAS2R14 with cholesterol and an intracellular tastant · A1AEI R501 · binds LEU348, LEU353, ALA100, GLY104, TYR107, PHE108, ILE111, SER194 and 11 more
- 8VY9 · CryoEM structure of Ggust-coupled TAS2R14 with cholesterol and an intracellular tastant · A1AEI R601 · binds LEU353, GLY104, TYR107, ILE111, SER194, MET197, PHE198, LEU201 and 7 more
- 8YKY · Structure of human class T GPCR TAS2R14-Ggustducin complex with agonist 28.1 · A1AEI R501 · binds LEU348, LEU353, ALA100, GLY104, TYR107, PHE108, SER194, MET197 and 9 more
- 9IJ9 · A Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex · A1AEI R501 · binds LEU348, LEU353, ALA100, LEU103, GLY104, TYR107, PHE108, SER194 and 10 more
- 9IJA · A local Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex · A1AEI R501 · binds ALA100, LEU103, GLY104, TYR107, PHE108, SER194, MET197, PHE198 and 8 more
Residues it binds most
GLY 5, LEU 5, PHE 5, SER 5, TYR 5, VAL 5, ALA 5, HIS 5, MET 5, ILE 2 (residue and the binding sites it lines).
Found with
- CLR · Cholesterol
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