Ligand · 8UF
8UF · 2-[1-[(3~{S})-6'-azanyl-5'-cyano-7-fluoranyl-2,2,3'-trimethyl-spiro[1~{H}-indene-3,4'-2~{H}-pyrano[2,3-c]pyrazole]-5-yl]piperidin-4-yl]ethanoic acid
8UF, 2-[1-[(3~{S})-6'-azanyl-5'-cyano-7-fluoranyl-2,2,3'-trimethyl-spiro[1~{H}-indene-3,4'-2~{H}-pyrano[2,3-c]pyrazole]-5-yl]piperidin-4-yl]ethanoic acid (C25 H28 F N5 O3, 465.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2…
- Component
- 8UF
- Formula
- C25 H28 F N5 O3
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
8UF in 2 structures; the first of them:
- 5YG4 · Plasmodium vivax SHMT bound with PLP-glycine and S-GS849 · 8UF A502 · binds LEU124, GLY127, GLY128, HIS129, LEU130, VAL141, THR183, SER184 and 10 more
- 5YG4 · Plasmodium vivax shmt bound with plp-glycine and S-GS849 · 8UF A502 · binds LEU124, GLY127, GLY128, HIS129, LEU130, VAL141, THR183, SER184 and 10 more
Residues it binds most
ASN 6, LEU 6, THR 6, GLY 6, TYR 4, ARG 6, CYS 6, HIS 6, LYS 6, SER 6 (residue and the binding sites it lines).
Found with
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