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Ligand · 8RI

8RI · (2E)-N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl) propyl]-3-(naphthalen-1-yl)prop-2-enamide

8RI, (2E)-N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl) propyl]-3-(naphthalen-1-yl)prop-2-enamide (C24 H26 N2 O2, 374.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
8RI
Formula
C24 H26 N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

8RI in 2 structures; the first of them:

  • 7SCG · FH210 bound Mu Opioid Receptor-Gi Protein Complex · 8RI D401 · binds THR120, GLN124, ASN127, TRP133, VAL143, ASP147, TYR148, MET151 and 6 more
  • 7SCG · FH210 bound mu opioid receptor-gi protein complex · 8RI D401 · binds GLN124, ASN127, VAL143, ASP147, MET151, CYS217, VAL236, ILE296 and 2 more

Residues it binds most

VAL 2, TYR 2, ASN 2, ASP 2, CYS 2, GLN 2, ILE 2, MET 2, LYS 1, THR 1 (residue and the binding sites it lines).

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