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Ligand · 8PZ

8PZ · [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-phenyl-propanoyl]sulfamate

8PZ, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-phenyl-propanoyl]sulfamate (C19 H23 N7 O7 S, 493.5 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB…

Component
8PZ
Formula
C19 H23 N7 O7 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

8PZ in 3 structures; the first of them:

  • 5N82 · Crystal structure of an engineered TycA variant in complex with an beta-Phe-AMP analog · 8PZ A503 · binds PHE232, ASP233, VAL234, TRP237, ALA299, GLY300, SER301, ALA302 and 11 more
  • 5N82 · Crystal structure of an engineered tyca variant in complex with an beta-phe-AMP analog · 8PZ A503 · binds PHE232, ASP233, VAL234, TRP237, ALA299, GLY300, SER301, ALA302 and 11 more
  • 7DQ5 · Crystal structure of hitb in complex with (S)-beta-phenylalanine sulfamoyladenosine · 8PZ A601 · binds PHE220, ASP221, PHE222, PHE225, THR293, GLY294, GLU295, ASP296 and 13 more

Residues it binds most

PHE 4, ALA 4, ASP 4, GLY 4, THR 4, ASN 4, TYR 4, VAL 2, ARG 2, GLU 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol
  • CA · Calcium ion

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