GL1X · GenesisL1 explorer

Ligand · 8OV

8OV · N-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide

8OV, N-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide (C27 H30 F3 N7 O3, 557.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every…

Component
8OV
Formula
C27 H30 F3 N7 O3
Class
ligand
Structures
1
PDB entries
1

Binding sites

8OV in 1 structure; the first of them:

  • 5UWD · Crystal structure of EGFR kinase domain (L858R, T790M, V948R) in complex with the… · 8OV A9001 · binds LEU718, VAL726, ALA743, LYS745, CYS775, MET790, GLN791, LEU792 and 9 more

Residues it binds most

LEU 1, CYS 1, MET 1, ALA 1, ARG 1, ASP 1, GLN 1, GLY 1, LYS 1, PHE 1 (residue and the binding sites it lines).

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