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Ligand · 8OP

8OP · [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate

8OP, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate (C10 H14 N5 O8 P, 363.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with…

Component
8OP
Formula
C10 H14 N5 O8 P
Class
ligand
Structures
4
PDB entries
2

Binding sites

8OP in 4 structures; the first of them:

  • 3MWK · Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP · 8OP B209 · binds PHE3, LEU21, THR23, PRO24, THR25, GLU28, GLY48, THR49 and 6 more
  • 3NBF · Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP · 8OP C501 · binds GLY109, TYR110, GLY111, LYS112, LYS114, TYR134, GLN137
  • 3MWK · Q28E mutant of hera N-terminal reca-like domain, complex with 8-oxo- AMP · 8OP B209 · binds PHE3, LEU21, THR23, PRO24, THR25, GLU28, GLY48, THR49 and 6 more
  • 3NBF · Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP · 8OP C501 · binds GLY109, TYR110, GLY111, LYS112, LYS114, TYR134, GLN137

Residues it binds most

THR 6, GLY 8, GLU 6, LEU 6, LYS 8, PHE 6, PRO 6, GLN 4, TYR 2, ARG 2 (residue and the binding sites it lines).

Found with

  • 8OD · [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate
  • SO4 · Sulfate ion

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