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Ligand · 8NK

8NK · 7-methylguanosine 5'-diphosphate

8NK, 7-methylguanosine 5'-diphosphate (C11 H18 N5 O11 P2 +1, 458.2 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
8NK
Formula
C11 H18 N5 O11 P2 +1
Class
ligand
Structures
5
PDB entries
5

Binding sites

8NK in 5 structures; the first of them:

  • 5N2V · Changes in conformational equilibria regulate the activity of the DCP2 decapping enzyme · 8NK B304 · binds TRP43, ASP47, LYS127, GLY128, LYS129, GLU143, GLU147, ARG190 and 2 more
  • 6WQ3 · Crystal structure of NSP16-NSP10 heterodimer from SARS-cov-2 in complex with… · 8NK A7103 · binds LEU6855, THR6856, ALA6986, TRP6987, CYS7007, ASN7008, SER7074
  • 7JPE · Room temperature structure of SARS-cov-2 NSP10/NSP16 methyltransferase in a complex with… · 8NK A303 · binds LEU57, THR58, ALA188, TRP189, CYS209, ASN210, SER276
  • 7SEZ · Crystal structure of vaccinia virus decapping enzyme D9 in complex with M7GDP · 8NK A301 · binds GLU16, HIS33, PHE35, ARG50, PHE54, GLN57, LYS112, ASP151 and 3 more
  • 7SF0 · Crystal structure of vaccinia virus decapping enzyme D9 in complex with trinucleotide… · 8NK A301 · binds GLU16, HIS33, PHE35, ARG50, PHE54, GLN57, LYS112, ASP151 and 3 more

Residues it binds most

GLU 4, LYS 4, PHE 2, ARG 4, ASP 4, TRP 4, ALA 2, ASN 2, CYS 2, GLN 2 (residue and the binding sites it lines).

Found with

  • GTA · P1-7-methylguanosine-P3-adenosine-5',5'-triphosphate
  • MG · Magnesium ion
  • NA · Sodium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion

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