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Ligand · 8K3

8K3 · 3-(2-azanylethyl)-1H-indole-5-carboxamide

8K3, 3-(2-azanylethyl)-1H-indole-5-carboxamide (C11 H13 N3 O, 203.2 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
8K3
Formula
C11 H13 N3 O
Class
ligand
Structures
5
PDB entries
3

Binding sites

8K3 in 5 structures; the first of them:

  • 7UM5 · CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT · 8K3 A401 · binds ASP121, VAL122, CYS125, THR126, VAL194, SER204, THR205, ALA208 and 6 more
  • 7X5H · Serotonin 5A (5-HT5A) receptor-Gi protein complex · 8K3 R601 · binds ASP121, VAL122, CYS125, THR126, VAL194, SER195, ALA201, SER204 and 7 more
  • 7XTC · Serotonin 7 (5-HT7) receptor-Gs-Nb35 complex · 8K3 R501 · binds ASP162, VAL163, CYS166, THR167, ILE213, ILE233, THR240, SER243 and 8 more
  • 7UM5 · Cryoem structure of go-coupled 5-HT5AR in complex with 5-ct · 8K3 A401 · binds ASP121, VAL122, CYS125, THR126, VAL194, SER204, GLU305, LEU324 and 1 more
  • 7XTC · Serotonin 7 (5-HT7) receptor-gs-NB35 complex · 8K3 R501 · binds ASP162, VAL163, CYS166, THR167, ILE233, THR240, SER243, THR244 and 5 more

Residues it binds most

THR 5, PHE 4, SER 5, VAL 5, ALA 4, ASP 5, CYS 5, LEU 5, TYR 4, GLU 3 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol

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