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Ligand · 81F

81F · 1-(5-bromopyridin-3-yl)-4-[cis-4-(3-methylphenyl) cyclohexyl]piperazine

81F, 1-(5-bromopyridin-3-yl)-4-[cis-4-(3-methylphenyl) cyclohexyl]piperazine (C22 H28 Br N3, 414.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
81F
Formula
C22 H28 Br N3
Class
ligand
Structures
2
PDB entries
1

Binding sites

81F in 2 structures; the first of them:

  • 7K4C · Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine… · 81F A701 · binds PRO424, PHE425, PHE456, VAL459, LEU460, CYS463, MET466, ILE482 and 5 more
  • 7K4C · Cryo-EM structure of human TRPV6 in complex with (4- PHENYLCYCLOHEXYL)PIPERAZINE… · 81F A701 · binds PRO424, PHE425, PHE456, VAL459, LEU460, CYS463, MET466, ILE482 and 5 more

Residues it binds most

ILE 10, PHE 8, ALA 10, CYS 8, GLN 8, GLY 2, LEU 6, MET 8, PRO 8, TRP 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion

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