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Ligand · 7R3

7R3 · (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3, 4,5-triol

7R3, (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3, 4,5-triol (C23 H27 Cl O7, 450.9 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every…

Component
7R3
Formula
C23 H27 Cl O7
Class
ligand
Structures
3
PDB entries
2

Binding sites

7R3 in 3 structures; the first of them:

  • 7VSI · Structure of human SGLT2-MAP17 complex bound with empagliflozin · 7R3 A703 · binds ASN75, GLY79, HIS80, GLY83, LEU84, THR87, VAL95, PHE98 and 16 more
  • 7Y0B · Crystal structure of human short-chain acyl-CoA dehydrogenase · 7R3 B502 · binds LYS62, MET370, THR374, GLU375, PRO157, ALA184, TRP185, LYS226 and 4 more
  • 7VSI · Structure of human SGLT2-MAP17 complex bound with empagliflozin · 7R3 A703 · binds ASN75, HIS80, GLY83, LEU84, THR87, VAL95, PHE98, GLU99 and 12 more

Residues it binds most

VAL 2, LEU 2, LYS 3, GLU 3, PHE 2, THR 3, TYR 2, ALA 3, ASN 3, ASP 3 (residue and the binding sites it lines).

Found with

  • PLM · Palmitic acid
  • FAD · Flavin-adenine dinucleotide

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