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Ligand · 7MR

7MR · (2R)-2-amino-3,3,3-trifluoro-N-hydroxy-2-{[(4-phenoxyphenyl)sulfonyl]methyl}propanamide

7MR, (2R)-2-amino-3,3,3-trifluoro-N-hydroxy-2-{[(4-phenoxyphenyl)sulfonyl]methyl}propanamide (C16 H15 F3 N2 O5 S, 404.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
7MR
Formula
C16 H15 F3 N2 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

7MR in 2 structures; the first of them:

  • 2OW1 · MMP-9 active site mutant with trifluoromethyl hydroxamate inhibitor · 7MR A501 · binds GLY186, LEU187, LEU188, ALA189, HIS190, LEU397, VAL398, HIS401 and 10 more
  • 2OW1 · Mmp-9 active site mutant with trifluoromethyl hydroxamate inhibitor · 7MR A501 · binds GLY186, LEU187, LEU188, ALA189, HIS190, LEU397, VAL398, HIS401 and 10 more

Residues it binds most

LEU 4, HIS 4, ALA 4, TYR 4, ARG 4, GLN 4, GLY 4, MET 4, PRO 4, VAL 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • CL · Chloride ion

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