GL1X · GenesisL1 explorer

Ligand · 6UA

6UA · 6-aminopyrimidine-2,4(3H,5H)-dione

6UA, 6-aminopyrimidine-2,4(3H,5H)-dione (C4 H5 N3 O2, 127.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
6UA
Formula
C4 H5 N3 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

6UA in 4 structures; the first of them:

  • 4WS2 · Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with… · 6UA A303 · binds GLY66, GLN67, ASP68, PRO69, TYR70, SER80, PHE81, SER93 and 2 more
  • 4WS3 · Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with… · 6UA A301 · binds GLY66, GLN67, ASP68, PRO69, TYR70, SER80, PHE81, SER93 and 1 more
  • 4WS2 · Crystal structure of mycobacterium tuberculosis uracil-DNA glycosylase in complex with… · 6UA A303 · binds GLY66, GLN67, ASP68, PRO69, TYR70, SER80, PHE81, SER93 and 2 more
  • 4WS3 · Crystal structure of mycobacterium tuberculosis uracil-DNA glycosylase in complex with… · 6UA A301 · binds GLY66, GLN67, ASP68, PRO69, TYR70, SER80, PHE81, SER93 and 1 more

Residues it binds most

SER 4, ASN 4, ASP 4, GLN 4, GLY 4, PHE 4, PRO 4, TYR 4, HIS 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • DMS · Dimethyl sulfoxide
  • CIT · Citric acid
  • IPA · Isopropyl alcohol

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