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Ligand · 5HN

5HN · 5-hydroxypyridine-3-carboxylic acid

5HN, 5-hydroxypyridine-3-carboxylic acid (C6 H5 N O3, 139.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
5HN
Formula
C6 H5 N O3
Class
ligand
Structures
2
PDB entries
2

Binding sites

5HN in 2 structures; the first of them:

  • 5HXI · 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5HN bound · 5HN A403 · binds TYR82, ARG211, LEU213, TYR223, MET227, TYR270, PRO295, ALA296 and 2 more
  • 5RST · Pandda analysis group deposition -- crystal structure of SARS-cov-2 NSP3 macrodomain in… · 5HN A201 · binds GLY48, VAL49, PRO125, GLY130, ILE131, VAL155, PHE156

Residues it binds most

TYR 1, ALA 1, GLY 1, LEU 1, PRO 2, VAL 1, ARG 1, ILE 1, MET 1, PHE 1 (residue and the binding sites it lines).

Found with

  • FAD · Flavin-adenine dinucleotide
  • NA · Sodium ion
  • BME · Beta-mercaptoethanol
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether

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