Ligand · 5DR
5DR · 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
5DR, 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine (C22 H22 N4 O, 358.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- 5DR
- Formula
- C22 H22 N4 O
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
5DR in 4 structures; the first of them:
- 3S9U · Bacillus anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP120J · 5DR A163 · binds MET6, VAL7, ALA8, ASN20, LEU21, GLU28, LEU29, VAL32 and 10 more
- 3SH2 · Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and… · 5DR A168 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 7 more
- 3S9U · Bacillus anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, UCP120J · 5DR A163 · binds MET6, VAL7, ALA8, ASN20, LEU21, GLU28, LEU29, VAL32 and 10 more
- 3SH2 · Staphylococcus aureus dihydrofolate reductase complexed with NADPH and… · 5DR A168 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 7 more
Residues it binds most
LEU 8, VAL 8, ALA 8, ASN 8, THR 8, PHE 8, ARG 4, ILE 8, ASP 4, GLN 4 (residue and the binding sites it lines).
Found with
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