Ligand · 53T
53T · 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
53T, 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (C24 H26 N4 O, 386.5 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its…
- Component
- 53T
- Formula
- C24 H26 N4 O
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
53T in 6 structures; the first of them:
- 3EEL · Candida glabrata Dihydrofolate Reductase complexed with… · 53T A229 · binds ILE9, VAL10, ALA11, GLY23, ASN24, LEU25, GLU32, MET33 and 10 more
- 3F0S · Staphylococcus aureus dihydrofolate reductase complexed with NADPH and… · 53T X158 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 9 more
- 3F0X · Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and… · 53T X158 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 10 more
- 3EEL · Candida glabrata dihydrofolate reductase complexed with 2,4-diamino-5… · 53T A229 · binds ILE9, VAL10, ALA11, GLY23, ASN24, LEU25, GLU32, MET33 and 10 more
- 3F0S · Staphylococcus aureus dihydrofolate reductase complexed with NADPH and… · 53T X158 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 9 more
- 3F0X · Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and… · 53T X158 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 10 more
Residues it binds most
LEU 8, ILE 8, THR 8, PHE 8, VAL 8, ALA 8, ASN 8, SER 8, TYR 6, ASP 4 (residue and the binding sites it lines).
Found with
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
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