Ligand · 53S
53S · 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
53S, 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (C23 H24 N4 O, 372.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…
- Component
- 53S
- Formula
- C23 H24 N4 O
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
53S in 4 structures; the first of them:
- 3EEK · Candida glabrata Dihydrofolate Reductase complexed with… · 53S A229 · binds ILE9, VAL10, ALA11, GLY23, ASN24, LEU25, GLU32, MET33 and 9 more
- 4H97 · Candida albicans dihydrofolate reductase complexed with NADPH and… · 53S A202 · binds ILE9, VAL10, ALA11, MET25, GLU32, ILE33, PHE36, LYS37 and 9 more
- 3EEK · Candida glabrata dihydrofolate reductase complexed with 2,4-diamino-5… · 53S A229 · binds ILE9, VAL10, ALA11, GLY23, ASN24, LEU25, GLU32, MET33 and 9 more
- 4H97 · Candida albicans dihydrofolate reductase complexed with NADPH and 5… · 53S A202 · binds ILE9, VAL10, ALA11, MET25, GLU32, ILE33, PHE36, LYS37 and 9 more
Residues it binds most
ILE 8, PHE 8, THR 8, ALA 8, GLU 8, LEU 8, MET 8, PRO 8, SER 8, TYR 8 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.