GL1X · GenesisL1 explorer

Ligand · 4HG

4HG · N-[(4-hydroxy-8-iodoisoquinolin-3-yl)carbonyl]glycine

4HG, N-[(4-hydroxy-8-iodoisoquinolin-3-yl)carbonyl]glycine (C12 H9 I N2 O4, 372.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
4HG
Formula
C12 H9 I N2 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

4HG in 4 structures; the first of them:

  • 2G19 · Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase… · 4HG A801 · binds ASP254, ILE256, MET299, TYR303, TYR310, HIS313, ASP315, ILE327 and 7 more
  • 2G1M · Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase… · 4HG A701 · binds ASP254, ILE256, MET299, TYR303, TYR310, HIS313, ASP315, ILE327 and 7 more
  • 2G19 · Cellular oxygen sensing: crystal structure of hypoxia-inducible factor prolyl hydroxylase… · 4HG A801 · binds ASP254, ILE256, MET299, TYR303, TYR310, HIS313, ASP315, ILE327 and 7 more
  • 2G1M · Cellular oxygen sensing: crystal structure of hypoxia-inducible factor prolyl hydroxylase… · 4HG A701 · binds ASP254, ILE256, MET299, TYR303, TYR310, HIS313, ASP315, ILE327 and 7 more

Residues it binds most

TYR 4, ASP 4, HIS 4, ILE 4, ALA 4, ARG 4, LEU 4, MET 4, TRP 4, VAL 4 (residue and the binding sites it lines).

Found with

  • FE2 · Fe (II) ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.