GL1X · GenesisL1 explorer

Ligand · 4G7

4G7 · 3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl) benzoic acid

4G7, 3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl) benzoic acid (C17 H14 F N O6, 347.3 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
4G7
Formula
C17 H14 F N O6
Class
ligand
Structures
8
PDB entries
6

Binding sites

4G7 in 8 structures; the first of them:

  • 6TXP · Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure… · 4G7 A402 · binds TRP20, VAL47, TYR48, TRP79, CYS80, HIS110, TRP111, THR113 and 9 more
  • 6Y1P · Human Aldose Reductase Mutant L300/301A in Complex with a Ligand with an IDD Structure… · 4G7 A401 · binds TRP20, VAL47, TYR48, TRP79, CYS80, HIS110, TRP111, THR113 and 7 more
  • 8B3N · Human Aldose Reductase Mutant A299G/L300G in Complex with a Ligand with an IDD Structure… · 4G7 A402 · binds TRP20, VAL47, TYR48, TRP79, CYS80, HIS110, TRP111, THR113 and 9 more
  • 8B66 · Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure… · 4G7 A403 · binds TRP20, VAL47, TYR48, HIS110, TRP111, PHE122, TRP219, CYS298 and 1 more
  • 8P2R · Human Aldose Reductase Mutant A299G/L300A in Complex with a Ligand with an IDD Structure… · 4G7 A403 · binds TRP20, VAL47, TYR48, HIS110, TRP111, PHE122, TRP219, CYS298 and 1 more
  • 6T7Q · Human aldose reductase mutant L301A in complex with a ligand with an idd structure… · 4G7 A401 · binds TRP20, VAL47, TYR48, TRP79, HIS110, TRP111, THR113, PHE122 and 4 more
  • 6TXP · Human aldose reductase mutant L300A in complex with a ligand with an idd structure… · 4G7 A402 · binds TRP20, VAL47, TYR48, TRP79, CYS80, HIS110, TRP111, THR113 and 7 more
  • 6Y1P · Human aldose reductase mutant L300/301A in complex with a ligand with an idd structure… · 4G7 A401 · binds TRP20, VAL47, TYR48, TRP79, CYS80, HIS110, TRP111, THR113 and 7 more

Residues it binds most

TRP 11, CYS 10, ALA 9, TYR 8, PHE 8, VAL 11, HIS 8, THR 6, LEU 3, ARG 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • CIT · Citric acid
  • 2WR · (2-carbamoyl-5-fluorophenoxy)acetic acid

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.