GL1X · GenesisL1 explorer

Ligand · 4DC

4DC · (2R)-3-cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide

4DC, (2R)-3-cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide (C18 H22 N2 O3 S2, 378.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
4DC
Formula
C18 H22 N2 O3 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

4DC in 2 structures; the first of them:

  • 4DCH · Insights into Glucokinase Activation Mechanism: Observation of Multiple Distinct Protein… · 4DC A502 · binds TYR61, VAL62, ARG63, SER64, THR65, PRO66, GLU67, GLN98 and 9 more
  • 4DCH · Insights into glucokinase activation mechanism: observation of multiple distinct protein… · 4DC A502 · binds TYR61, VAL62, ARG63, SER64, THR65, PRO66, GLU67, GLN98 and 9 more

Residues it binds most

LYS 2, MET 2, TYR 2, VAL 2, ARG 2, GLN 2, GLU 2, ILE 2, LEU 2, PRO 2 (residue and the binding sites it lines).

Found with

  • GLC · alpha-D-glucopyranose
  • IOD · Iodide ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.