4BW · 2-amino-9-[(2r,3r,3as,5r,7ar,9r,10r,10as,12r,14ar)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-D:3',2'-J][1,3,7,9, 2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one

Binding sites

4BW in 8 structures; the first of them:

• 6IH7 · Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395… · 4BW B301 · binds GLN31, GLU45, ALA46, LEU47, VAL48, ARG49, ALA56, ILE60 and 13 more
• 5VDT · Human cyclic gmp-AMP synthase (cgas) in complex with 3',3'-cgamp · 4BW A602 · binds ASP227, MET229, GLY304, SER305, PRO306, ALA307, THR321, LYS362 and 6 more
• 6AEL · Crystal structure of ENPP1 in complex with 3'3'-cgamp · 4BW A1007 · binds LYS237, ALA238, PHE239, ASN259, LEU272, LYS273, LYS277, TRP304 and 9 more
• 6IH7 · Crystal structure of a standalone versatile eal protein from vibrio cholerae O395… · 4BW B301 · binds GLN31, GLU45, ALA46, LEU47, VAL48, ARG49, ALA56, ILE60 and 13 more
• 6WT4 · Structure of a bacterial sting receptor from flavobacteriaceae sp. in complex with… · 4BW A301 · binds GLY87, TYR88, ASN91, PHE92, ARG153, ILE155, LEU156, THR157 and 13 more
• 6YDZ · Human wtsting in complex with 3',3'-cgamp · 4BW A401 · binds SER162, TYR163, GLY166, TYR167, ARG232, ILE235, ARG238, VAL239 and 4 more
• 6YJ9 · Darb in complex with 3'3'CGAMP · 4BW A201 · binds LYS23, VAL24, ALA25, TYR45, THR46, ALA47, ILE48, GLY114 and 7 more
• 7UNA · Sfsting with cgamp (masked) · 4BW A401 · binds TYR161, SER164, PHE165, PHE236, PRO237, ASP259, SER262, THR263 and 9 more

Residues it binds most

TYR 17, PHE 9, SER 8, ARG 12, THR 10, ASP 12, GLY 12, PRO 13, ALA 9, GLU 5 (residue and the binding sites it lines).

Found with

• CA · Calcium ion
• ZN · Zinc ion
• CL · Chloride ion
• MAN · alpha-D-mannopyranose
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• SO4 · Sulfate ion
• EDO · 1,2-ethanediol