Ligand · 4BM
4BM · N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
4BM, N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide (C16 H14 F3 I N2 O4, 482.2 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its…
- Component
- 4BM
- Formula
- C16 H14 F3 I N2 O4
- Class
- ligand
- Structures
- 3
- PDB entries
- 3
Binding sites
4BM in 3 structures; the first of them:
- 7JUU · Crystal structure of KSR2:MEK1 in complex with AMP-pnp, and allosteric MEK inhibitor… · 4BM C402 · binds LYS97, LEU115, LEU118, VAL127, ILE141, MET143, ASP208, PHE209 and 5 more
- 7JV0 · Crystal structure of KSR1:MEK1 in complex with AMP-pnp, and allosteric MEK inhibitor… · 4BM C402 · binds GLY77, LYS97, ILE99, LEU118, VAL127, ILE141, MET143, ASP208 and 6 more
- 7M0X · Crystal structure of the BRAF:MEK1 kinases in complex with amppnp and PD0325901 · 4BM B803 · binds GLY77, ASN78, GLY79, GLY80, LYS97, LEU115, LEU118, VAL127 and 11 more
Residues it binds most
LEU 3, GLY 3, MET 3, VAL 3, ILE 3, ASP 3, LYS 3, PHE 3, SER 3, ASN 1 (residue and the binding sites it lines).
Found with
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