GL1X · GenesisL1 explorer

Ligand · 3UW

3UW · (4S,4a'S,10a'R)-2-amino-8'-(2-fluoropyridin-3-yl)-1-methyl-3',4',4a',10a'-tetrahydro-2'H-spiro[imidazole-4,10'-pyrano[3,2-b]chromen]-5(1H)-one

3UW, (4S,4a'S,10a'R)-2-amino-8'-(2-fluoropyridin-3-yl)-1-methyl-3',4',4a',10a'-tetrahydro-2'H-spiro[imidazole-4,10'-pyrano[3,2-b]chromen]-5(1H)-one (C20 H19 F N4 O3, 382.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
3UW
Formula
C20 H19 F N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

3UW in 2 structures; the first of them:

  • 4RRN · 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein… · 3UW A502 · binds GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96, VAL130 and 11 more
  • 4RRN · 8-tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein… · 3UW A502 · binds GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96, VAL130 and 11 more

Residues it binds most

GLY 2, ASP 2, ILE 2, SER 2, THR 2, TRP 2, GLN 2, LEU 2, PHE 2, TYR 2 (residue and the binding sites it lines).

Found with

  • NI · Nickel (II) ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.