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Ligand · 3TZ

3TZ · N-[(4-{[(2-amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid

3TZ, N-[(4-{[(2-amino-4-oxo-3,4-dihydro[1]benzothieno[2,3-d]pyrimidin-5-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid (C23 H21 N5 O6 S, 495.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
3TZ
Formula
C23 H21 N5 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

3TZ in 2 structures; the first of them:

  • 3NTZ · Design, Synthesis, Biological Evaluation and X-ray Crystal Structures of Novel Classical… · 3TZ A187 · binds ILE7, VAL8, ALA9, LEU22, GLU30, PHE31, ARG32, PHE34 and 11 more
  • 3NTZ · Design, synthesis, biological evaluation and X-ray crystal structures of novel classical… · 3TZ A187 · binds ILE7, VAL8, ALA9, LEU22, GLU30, PHE31, ARG32, PHE34 and 11 more

Residues it binds most

ARG 2, ILE 2, LEU 2, PHE 2, THR 2, VAL 2, ALA 2, ASN 2, GLN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • SO4 · Sulfate ion

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