3OX · (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4R,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide

Binding sites

3OX in 2 structures; the first of them:

• 3OWN · Potent macrocyclic renin inhibitors · 3OX A500 · binds GLN16, ASP35, GLY37, SER38, ARG79, TYR80, SER81, THR82 and 20 more
• 3OWN · Potent macrocyclic renin inhibitors · 3OX A500 · binds GLN16, ASP35, GLY37, SER38, ARG79, TYR80, SER81, THR82 and 20 more

Residues it binds most

SER 2, ALA 2, ILE 2, ASP 2, GLN 2, GLY 2, LEU 2, PHE 2, TYR 2, ARG 2 (residue and the binding sites it lines).

Found with

• 3OW · (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4S,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide
• NA · Sodium ion
• ACT · Acetate ion