3OW · (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4S,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide

Binding sites

3OW in 2 structures; the first of them:

• 3OWN · Potent macrocyclic renin inhibitors · 3OW B501 · binds THR15, GLN16, TYR17, VAL33, ASP35, GLY37, SER38, ARG79 and 23 more
• 3OWN · Potent macrocyclic renin inhibitors · 3OW B501 · binds THR15, GLN16, TYR17, VAL33, ASP35, GLY37, SER38, ARG79 and 23 more

Residues it binds most

SER 2, TYR 2, ALA 2, ILE 2, THR 2, ASP 2, GLN 2, GLY 2, PHE 2, VAL 2 (residue and the binding sites it lines).

Found with

• 3OX · (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4R,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide
• NA · Sodium ion
• ACT · Acetate ion