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Ligand · 3JF

3JF · N-acetyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide

3JF, N-acetyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide (C24 H32 N4 O4 S, 472.6 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its…

Component
3JF
Formula
C24 H32 N4 O4 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

3JF in 3 structures; the first of them:

  • 4W9H · pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy… · 3JF C301 · binds ASN67, ARG69, PHE76, PRO86, TRP88, PHE91, TYR98, PRO99 and 9 more
  • 8VLB · Crystal structure of EloBC-VHL-CDO1 complex bound to compound 4 molecular glue · 3JF A301 · binds ARG69, PHE76, PRO86, TRP88, PHE91, TYR98, PRO99, LEU101 and 16 more
  • 4W9H · PVHL:ELOB:ELOC in complex with (2S,4R)-1-((S)-2-acetamido-3,3… · 3JF C301 · binds ASN67, ARG69, PHE76, PRO86, TRP88, PHE91, TYR98, PRO99 and 9 more

Residues it binds most

PRO 9, PHE 9, TRP 9, HIS 9, TYR 9, ARG 9, ILE 9, LEU 9, SER 9, ASN 8 (residue and the binding sites it lines).

Found with

  • FE2 · Fe (II) ion
  • CIT · Citric acid

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