GL1X · GenesisL1 explorer

Ligand · 3HG

3HG · 3-hydroxypentanedioic acid

3HG, 3-hydroxypentanedioic acid (C5 H8 O5, 148.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
3HG
Formula
C5 H8 O5
Class
ligand
Structures
4
PDB entries
2

Binding sites

3HG in 4 structures; the first of them:

  • 2CW6 · Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis… · 3HG A399 · binds ARG41, GLN45, VAL82, LEU106, PHE127
  • 3MP3 · Crystal Structure of Human Lyase in complex with inhibitor HG-CoA · 3HG A400 · binds ARG41, ASP42, GLN45, LEU106, PHE127, TYR167, HIS233, HIS235
  • 2CW6 · Crystal structure of human hmg-CoA lyase: insights into catalysis and the molecular basis… · 3HG A399 · binds ARG41, GLN45, VAL82, LEU106, PHE127
  • 3MP3 · Crystal structure of human lyase in complex with inhibitor hg-CoA · 3HG A400 · binds ARG41, ASP42, GLN45, LEU106, PHE127, TYR167, HIS233, HIS235

Residues it binds most

ARG 4, GLN 4, HIS 2, LEU 4, PHE 4, ASP 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • HGG · (3R,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.