Ligand · 2V8
2V8 · 1-(5-chloro-2-methylphenyl)-5-(3-chlorophenyl)-2-(3-methylphenyl)-1H-imidazole-4-carboxylic acid
2V8, 1-(5-chloro-2-methylphenyl)-5-(3-chlorophenyl)-2-(3-methylphenyl)-1H-imidazole-4-carboxylic acid (C24 H18 Cl2 N2 O2, 437.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…
- Component
- 2V8
- Formula
- C24 H18 Cl2 N2 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
2V8 in 2 structures; the first of them:
- 4OQ3 · Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction · 2V8 A201 · binds LEU54, LEU57, GLY58, ILE61, MET62, TYR67, GLN72, VAL75 and 7 more
- 4OQ3 · Tetra-substituted imidazoles as a new class of inhibitors of the P53- MDM2 interaction · 2V8 A201 · binds LEU54, LEU57, GLY58, ILE61, MET62, TYR67, GLN72, VAL75 and 7 more
Residues it binds most
TYR 8, ILE 8, LEU 8, PHE 8, VAL 8, GLN 8, GLY 8, HIS 8, LYS 8, MET 8 (residue and the binding sites it lines).
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