MolNFT v2 · #102599 · protein
Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction
4OQ3: “Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction”. X-ray diffraction at 2.3. MolNFT v2 #102599 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4OQ3
- Type
- protein
- Length
- 367 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.3
- Source
- Homo sapiens
- UniProt
- Q00987
Structure
x-ray diffraction · resolution 2.3 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 93 | — | Q00987 |
| B | — | protein | 91 | — | Q00987 |
| D | — | protein | 90 | — | Q00987 |
Compared structures
- 4OQ3 · Tetra-substituted imidazoles as a new class of inhibitors of the P53- MDM2 interaction · the same entry in another collection · chain A against A, TM-score 1.00
- Q00987 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase MDM2 (Q00987) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00987
- Elsewhere: RCSB PDB 4OQ3 · PDBe 4OQ3 · UniProt Q00987
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