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Ligand · 2UC

2UC · 1-[3-(2-oxoethyl)benzyl]guanidine

2UC, 1-[3-(2-oxoethyl)benzyl]guanidine (C10 H13 N3 O, 191.2 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
2UC
Formula
C10 H13 N3 O
Class
ligand
Structures
3
PDB entries
3

Binding sites

2UC in 3 structures; the first of them:

  • 4OMC · X-ray structure of human furin in complex with the competitive inhibitor… · 2UC H1 · binds VAL231, THR232, ASP233, GLU236, GLY255, PRO256, GLU257, ASP264 and 4 more
  • 5JXH · Structure the proprotein convertase furin in complex with meta… · 2UC H1 · binds VAL231, THR232, ASP233, GLU236, GLY255, PRO256, GLU257, ASP264 and 4 more
  • 5JXJ · Structure of the proprotein convertase furin complexed to meta… · 2UC H1 · binds VAL231, THR232, ASP233, GLU236, GLY255, PRO256, GLU257, ASP264 and 4 more

Residues it binds most

ASP 8, GLU 8, VAL 8, ALA 8, ARG 8, GLY 8, PRO 8, THR 8, TYR 8 (residue and the binding sites it lines).

Found with

  • 00S · 4-(aminomethyl)benzenecarboximidamide
  • CA · Calcium ion
  • NA · Sodium ion
  • CL · Chloride ion
  • FMT · Formic acid

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