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Ligand · 2PX

2PX · N-{1-[(5-methyl-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide

2PX, N-{1-[(5-methyl-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide (C26 H31 N5 O, 429.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
2PX
Formula
C26 H31 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

2PX in 2 structures; the first of them:

  • 4NYI · Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide… · 2PX S1101 · binds MET878, ASN879, VAL883, TYR884, ASP887, PHE890, LYS898, LEU901 and 2 more
  • 4NYI · Approach for targeting RAS with small molecules that activate sos- mediated nucleotide… · 2PX S1101 · binds MET878, ASN879, VAL883, TYR884, ASP887, PHE890, LYS898, LEU901 and 2 more

Residues it binds most

ASN 2, ASP 2, GLU 2, HIS 2, LEU 2, LYS 2, MET 2, PHE 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • GNP · Phosphoaminophosphonic acid-guanylate ester
  • MG · Magnesium ion

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