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Ligand · 2G4

2G4 · N-[(S)-hydroxy(4-phenylbutoxy)phosphoryl]-L-glutamic acid

2G4, N-[(S)-hydroxy(4-phenylbutoxy)phosphoryl]-L-glutamic acid (C15 H22 N O7 P, 359.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
2G4
Formula
C15 H22 N O7 P
Class
ligand
Structures
2
PDB entries
1

Binding sites

2G4 in 2 structures; the first of them:

  • 4P4E · X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a… · 2G4 A822 · binds PHE209, ARG210, ASN257, HIS377, ASP387, GLU424, GLU425, GLY427 and 15 more
  • 4P4E · X-ray structure of human glutamate carboxypeptidase II (gcpii) in complex with a… · 2G4 A822 · binds PHE209, ARG210, ASN257, HIS377, ASP387, GLU424, GLU425, GLY427 and 15 more

Residues it binds most

GLU 2, GLY 2, TYR 2, ARG 2, ASN 2, ASP 2, HIS 2, LYS 2, PHE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • FUC · alpha-L-fucopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • CL · Chloride ion

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